Safety Announcement Additional Information for Patients Additional Information for Healthcare Professionals Data Summary Safety Announcement [07-08-2010] Due to continued reports of serious side effects in patients using Qualaquin “off-label” (a non-FDA-approved use) for night time leg cramps, the U.S. Food and Drug Administration (FDA) has approved a risk management plan to warn against the…
Hypertension Indication: Drug Labeling for Cardiovascular Outcome Claims
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FDA Drug Safety Communication: FDA warns about several safety issues with opioid pain medicines; requires label changes
FDA investigated several safety issues associated with the class of opioid pain medicines: Serotonin syndrome Adrenal insufficiency Androgen deficiency Serotonin syndrome A search of the FDA Adverse Event Reporting System (FAERS) database for the period January 1, 1969, to June 12, 2013, identified 43 cases of serotonin syndrome in which opioids were used concomitantly with…
FDA Statement on Avandia TIDE Trial
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FDA Drug Safety Communication: Risk of oral clefts in children born to mothers taking Topamax (topiramate)
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FDA Drug Safety Communication: New warnings against use of terbutaline to treat preterm labor
Safety AnnouncementAdditional Information for PatientsAdditional Information for Healthcare ProfessionalsData Summary References Safety Announcement [02-17-2011] The U.S. Food and Drug Administration (FDA) is warning the public that injectable terbutaline should not be used in pregnant women for prevention or prolonged treatment (beyond 48-72 hours) of preterm labor in either the hospital or outpatient setting because of…
FDA reminder to avoid concomitant use of Plavix (clopidogrel) and omeprazole
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FDA Statement on ASBMR report: Possible Increased Risk of Certain Types of Thigh Bone Fractures with Long-Term Bisphosphonates Use
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Q3D Elemental Impurities
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Q11 Development and Manufacture of Drug Substances
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